原著論文・総説/解説・書籍
2023年
Watabe, Y., Takahashi, S. (2023) Production of enhanced carotenoid-producing strains of the yeast Rhodotorula gracilis using the antibiotic Zeocine. Appl Biochem Biotech, https://doi.org/10.1007/s12010-023-04494-x.
Imanishi, D., Takahashi, S. (2023) RNA sequencing data analysis of the yeast Vanrija (Cryptococcus) humicola strain UJ1 grown on L- and D-aspartate. Data in brief, 47:109008. https://doi.org/10.1016/j.dib.2023.109008.
2022年
Kajitani K., Ishikawa T., Kobayashi T., Asato M., Shibata K., Kouya T., Takahashi S. (2022) Mechanism of high D-aspartate production in the lactic acid bacterium Latilactobacillus sp. strain WDN19. Appl Microbiol Biotechnol, 106(7), 2651-2663. https://doi.org/10.1007/s00253-022-11870-w.
2021年
Imanishi, D.; Zaitsu, S, Takahashi, S. (2021) Regulation of D-Aspartate Oxidase Gene Expression by Pyruvate Metabolism in the Yeast Cryptococcus humicola. Microorganisms, 9, 2444. https://doi.org/10.3390/microorganisms9122444
Kajitani K and Takahashi S. (2021) Complete genome sequence of Latilactobacillus sp. strain WDN19, a high-D-aspartate-producing lactic acid bacterium isolated from a Japanese pickle. Microbiol Resour Announc, 10(34), https://doi.org/10.1128/MRA.00568-21.
Kajitani K, Ishikawa T, Shibata K, Kouya T, Kera Y, Takahashi S. (2021) Development of an enzymatic screening method for D-aspartate-producing lactic acid bacteria. Enzyme Microbial Tech, 149, 109835, 2021. https://doi.org/10.1016/j.enzmictec.2021.109835
高橋祥司. (2021). 難分解性有機リン系難燃可塑剤の微生物分解代謝と無害化: 含塩素有機リン系難燃可塑剤による環境汚染の浄化に向けて. 化学と生物: 日本農芸化学会会誌: 生命・食・環境, 59(9), 441-448. https://katosei.jsbba.or.jp/index.php?aid=1473
Imanishi D, Kera Y, Takahashi S. (2021) Identification of an acidic amino acid permease involved in D-aspartate uptake in the yeast Cryptococcus humicola. Microorganisms, 9(1), 192. https://doi.org/10.3390/microorganisms9010192
2020年
Shimekake Y, Hirato Y, Funabashi R, Okazaki S, Goto M, Furuichi T, Suzuki H, Kera Y, Takahashi S. (2020) X-ray structure analysis of a unique D-amino acid oxidase of the thermophilic fungus Rasamsonia emersonii strain YA. Acta Crystallogr. F Struct. Biol. Commun. 76(11), 517-523. https://doi.org/10.1107/S2053230X20013333
Shibata K, Imanishi D, Abe K, Suzuki M, Takahashi S, Kera Y. (2020) D-Aspartate N-methyltransferase catalyzes biosynthesis of N-methyl-D-aspartate (NMDA), a well-known selective agonist of the NMDA receptor, in mice. BBA - PROTEINS PROTEOM. In press. https://doi.org/10.1016/j.bbapap.2020.140527
Takahashi S. (2020) D-Aspartate oxidase: distribution, functions, properties, and biotechnological applications. Appl. Microbiol. Biotechnol., 104: 2883-2895. https://doi.org/10.1007/s00253-020-10439-9
Takahashi S, Morooka Y, Kumakura T, Abe K, Kera Y. (2020) Enzymatic characterization and regulation of gene expression of PhoK alkaline phosphatase in Sphingobium sp. strain TCM1. Appl. Microbiol. Biotechnol., 104, 1125-1134. https://doi.org/10.1007/s00253-019-10291-6
2019年
Shibata K, Hagiya S, Okawara R, Abe K, Takahashi S, Kera Y. (2019) Liquid chromatography-electrospray ionization-tandem mass spectrometric assay for d-aspartate N-methyltransferase activity in ark shells. Biosci. Biotech. Biochem., 84(3): 500-506. https://doi.org/10.1080/09168451.2019.1689094
Shibata K, Sugaya N, Kuboki Y, Matsuda H, Abe K, Takahashi S, Kera Y. (2019) Aspartate racemase and D-aspartate in starfish; possible involvement in testicular maturation. Biosci. Biotech. Biochem., 84(1), 952019, https://doi.org/10.1080/09168451.2019.1660614
Shimekake Y, Furuichi T, Abe K, Kera Y, Takahashi S. (2019) A novel thermostable D-amino acid oxidase of the thermophilic fungus Rasamsonia emersonii strain YA. Sci. Rep., 2019, 9: 11948. https://doi.org/10.1038/s41598-019-48480-y
Takahashi S, Osugi K, Shimekake Y, Shinbo A, Abe K, Kera Y. (2019) Characterization and improvement of substrate-binding affinity of D-aspartate oxidase of the thermophilic fungus Thermomyces dupontii. Appl. Microbiol. Biotechnol., 103(10), 4053-4064. https://doi.org/10.1007/s00253-019-09787-y
2018年
Imanishi D, Abe K, Kera Y, Takahashi S. (2018) Draft Genome Sequence of the Yeast Vanrija humicola (Formerly Cryptococcus humicola) Strain UJ1, a Producer of D-Aspartate Oxidase. Genome Announc. 6(11):e00068-18. doi:10.1128/genomeA.00068-18
2017年
Takahashi, S., Abe, K., Shibata, K., Kera, Y. (2017) Functions and metabolism of D-amino acids in microorganisms. In: The handbook of microbial metabolism of amino acids (D'Mello, J.P.F., Editor)., CAB International, Wallingford, UK, pp.315-331. DOI: 10.1079/9781780647234.0315.
Mizobuchi, T., Nonaka, R., Yoshimura, M., Abe, K., Takahashi, S., Kera, Y., Goto, M. (2017) Crystal structure of a pyridoxal 5′-phosphate-dependent aspartate racemase derived from the bivalve mollusc Scapharca broughtonii. Acta Cryst., F73, 651-656. https://doi.org/10.1107/S2053230X17015813
Abe，K., Mukai, N., Morooka, Y., Makino, T., Oshima, K., Takahashi, S., Kera, Y. (2017) An atypical phosphodiesterase capable of degrading haloalkyl phosphate diesters from Sphingobium sp. strain TCM1. Sci. Rep., 7, 2842. https://doi.org/10.1038/s41598-017-03142-9
2016年
Takayama, K., Sakamoto, C., Takahashi, S., Abe, K., Hirobe, A., Koshigiri, T. (2016) Construction of a D-valine sensor using D-amino acid oxidase of Rubrobacter xylanophilus. J. Technology and Education, 23, 57-61.
Takahashi, S., Katanuma, H., Abe, K., Kera, Y. (2016) Identification of alkaline phosphatase genes for utilizing a flame retardant, tris(2-chloroethyl) phosphate, in Sphingobium sp. strain TCM1. Appl. Microbiol. Biotechnol.,101, 2153-2162. https://doi.org/10.1007/s00253-016-7991-9
Kera, Y., Abe, K., Kasai, D., Fukuda, M., Takahashi, S. (2016) Draft genome sequences of Sphingobium sp. strain TCM1 and Sphingomonas sp. strain TDK1, haloalkyl phosphate flame retardant and plasticizer-degrading bacteria. Genome Announc.,4, e00668-16. doi: 10.1128/genomeA.00668-16
Takahashi, S., Shimada, K., Nozawa, S., Goto, M., Abe, K., Kera, Y. (2016) Possible role of a histidine residue in the substrate specificity of yeast D-aspartate oxidase. J. Biochem., 159, 371-378. https://doi.org/10.1093/jb/mvv108
2015年以前
Takahashi S, Abe K, Kera Y. (2015) Bacterial D-amino acid oxidases: Recent findings and future perspectives. Bioengineered, 6(4): 237-241. https://doi.org/10.1080/21655979.2015.1052917.
Takahashi, S., Furukawara, M., Omae, K., Tadokoro, N., Saito, Y., Abe, K. and Kera, Y. (2014) A highly stable D-amino acid oxidase of the thermophilic bacterium Rubrobacter xylanophilus. Appl. Environ. Microbiol., 80, 7219-7229. DOI: 10.1128/AEM.02193-14
Takahashi, S., Okada, H., Abe, K. and Kera, Y. (2014) Genetic transformation of the yeast Rhodotorula gracilis ATCC 26217 by electroporation. Appl. Biochem. Microbiol., 50, 624-628. https://doi.org/10.1134/S0003683814110040
Abe, K., Yoshida, Y., Suzuki, Y., Mori, J., Doi, Y., Takahashi, S. and Kera, Y. (2014) Haloalkylphosphorus hydrolases purified from Sphingomonas sp. strain TDK1 and Sphingobium sp. strain TCM1. Appl. Environ. Microbiol., 80, 5866-5873. DOI: 10.1128/AEM.01845-14https://aem.asm.org/content/80/18/5866.long
Saito, Y., Takahashi, S., Kobayashi, M., Abe, K. and Kera, Y. (2014) D-Amino acid oxidase of Streptomyces coelicolor and the effect of D-amino acids on the bacterium. Annal. Microbiol., 64, 1167-1177. https://doi.org/10.1007/s13213-013-0756-0
Takahashi, S., Okada, H., Abe, K. and Kera, Y. (2012) D-amino acid-induced expression of D-amino acid oxidase in the yeast Schizosaccharomyces pombe. Curr. Microbiol., 65, 764-769. https://doi.org/10.1007/s00284-012-0227-z
Kato, S., Ikuta, T., Hemmi, H., Takahashi, S., Kera, Y. and Yoshimura, T. (2012) Enzymatic assay for D-aspartic acid using D-aspartate oxidase and oxaloacetate decarboxylase. Biosci. Biotechnol. Biochem., 76, 2150-2152. https://doi.org/10.1271/bbb.120477
Takahashi, S., Miura, K., Abe, K. and Kera, Y. (2012) Complete detoxification of tris(2-chloroethyl) phosphate by two bacterial strains: Sphingobium sp. strain TCM1 and Xanthobacter autotrophicus strain GJ10. J. Biosci. Bioeng., 114, 306-311. https://doi.org/10.1016/j.jbiosc.2012.04.010
Takahashi, S., Obana, Y., Okada, S., Abe, K. and Kera, Y. (2012) Complete detoxification of tris(1,3-dichloro-2-propyl) phosphate by mixed two bacteria, Sphingobium sp. strain TCM1 and Arthrobacter sp. strain PY1. J. Biosci. Bioeng., 113, 79-83. https://doi.org/10.1016/j.jbiosc.2011.08.020
Shibata K., Sugaya N., Ono W., Abe K., Takahashi S. and Kera Y. (2011) Determination of D-aspartate N-methyltransferase activity in the starfish by direct analysis of N-methyl-D-aspartate with high-performance liquid chromatography. J. Chromatogr. B., 879, 3229-3234. https://doi.org/10.1016/j.jchromb.2011.02.035
Takahashi S., Nakajima Y., Imaizumi T., Furuta Y., Ohshiro Y., Abe K., Yamada R. and Kera Y. (2011) Development of an autonomously replicating linear vector of the yeast Cryptococcus humicola by using telomere-like sequence repeats. Appl. Microbiol. Biotechnol., 89, 1213-1221. https://doi.org/10.1007/s00253-010-2985-5
Takahashi, S., Satake, I., Konuma, I., Kawashima, K., Kawasaki, M., Mori, S., Morino, J., Mori, J., Xu, H., Abe, K., Yamada, R. and Kera, Y. (2010) Isolation and identification of persistent chlorinated organophosphorus flame retardants-degrading bacteria., Appl. Environ. Microbiol., 76, 5292-5296. DOI: 10.1128/AEM.00506-10
Takahashi, S., Matsumoto, S., Maruyama, K., Wakaizumi, A., Abe, K., Kera,Y. and Yamada, R. (2009) An active-site mutation enhances the catalytic activity of the yeast Cryptococcus humicola D-aspartate oxidase. J. Mol. Catal. B: Enzymatic, 61, 235-240. https://doi.org/10.1016/j.molcatb.2009.07.011
Sato, R., Matsumoto, T., Hidaka, N., Imai, Y., Abe, K., Takahashi, S., Yamada, R. and Kera,Y. (2009) Cloning and expression of carp acetylcholinesterase gene in Pichia pastoris and characterization of the recombinant enzyme. Protein Expr. Purif., 64, 205-212. https://doi.org/10.1016/j.pep.2008.12.003
Takahashi, S., Kawashima, K., Kawasaki, M., Kamito, J., Endo, Y., Akatsu, K., Horino, S., Yamada, R. and Kera, Y. (2008) Enrichment and characterization of chlorinated oganophosphate esters-degrading mixed bacterial cultures. J. Biosci. Bioeng., 106, 27-32. DOI: 10.1263/jbb.106.27
Sato, R., Mitani, K., Matsumoto, T., Takahashi, S., Yamada, R. and Kera, Y. (2007) Effects of insecticides in vitro on acetylcholinesterase purified from body muscle of Koi carp (Cyprinus carpio). Jpn. J. Environ. Toxicol., 10, 31-38. https://doi.org/10.11403/jset.10.31
Abe, K., Takahashi, S., Muroki, Y., Kera, Y. and Yamada, R. (2006) Cloning and expression of the pyridoxal 5'-phosphate-dependent aspartate racemase gene from the bivalve mollusk Scapharca broughtonii and characterization of the recombinant enzyme. J. Biochem., 139, 235-244. https://doi.org/10.1093/jb/mvj028
Takahashi, S., Kakuichi, T., Fujii, K., Kera, Y. and Yamada, R. (2005) Physiological role of D-aspartate oxidase in the assimilation and detoxification of D-aspartate in the yeast Cryptococcus humicola. Yeast, 22, 1203-1212. https://doi.org/10.1002/yea.1303
Watanabe, T., Shibata, K., Kera, Y., Takahashi, S. and Yamada, R. (2005) Effects of hypoxic and osmottic stress on the free D-aspartate level in the muscle of blood shell Scapharca broughtonii. Amino Acids, 28, 291-296. https://doi.org/10.1007/s00726-005-0188-7
Oshima, K., Nakajima, H., Takahashi, S., Kera, Y., Shimomura, M. and Miyauchi, S. (2005) Quartz crystal microbalance assay for determination of plasma vitellogenin. Sensors and Actuators B, 105, 473-478. https://doi.org/10.1016/j.snb.2004.07.005
Kera, Y., Mitani, K., Matsumoto, T., Sato, R., Takahashi, S. and Yamada, R. (2004) Acetylcholinesterase from Koi carp body muscle: tissue distribution, purification and characterization. Jpn. J. Environ. Toxicol., 7, 35-47. https://doi.org/10.11403/jset.7.35
Takahashi, S., Takahashi, T., Kera, R., Matsunaga, R., Shibuya, H. and Yamada, R. (2004) Cloning and expression in Escherichia coli of the D-aspartate oxidase gene from the yeast Cryptococcus humicola and characterization of the recombinant enzyme. J. Biochem., 135, 533-540. https://doi.org/10.1093/jb/mvh068
Takahashi, S., Matsunaga, R., Kera, Y. and Yamada, R. (2003) Isolation of the Cryptococcus humicolus URA3 gene encoding orotidine-5'-phosphate decarboxylase and its use as a selective marker for transformation. J. Biosci. Bioeng., 96, 23-31.
Shibata, K., Watanabe, T., Yoshikawa, H., Abe K., Takahashi, S., Kera, Y. and Yamada, R. (2003) Nucleotides modulate the activity of aspartate racemase of Scapharca broughtonii. Comp. Biochem. Physiol. Part B, 134, 713-719.
Shibata, K., Watanabe, T., Yoshikawa, H., Abe, K., Takahashi, S., Kera, Y. and Yamada, R. (2003) Purification and characterization of aspartate racemase from the bivalve mollusk Scapharca broughtonii. Comp. Biochem. Physiol. Part B, 134, 307-314. https://doi.org/10.1016/S1096-4959(02)00267-1
Tarui, A., Shibata, K., Takahashi, S., Kera, Y., Munegumi, T. and Yamada, R. (2003) N-Methyl-D-glutamate and N-methyl-L-glutamate in Scapharca broughtonii (Mollusca) and other invertebrates. Comp. Biochem. Physiol. Part B, 134, 79-87. https://doi.org/10.1016/S1096-4959(02)00231-2
Fujita, Y., Takahashi, S., Ueda, M., Tanaka, A., Okada, H., Morikawa, Y., Kawaguchi, T., Arai, M., Fukuda, H. and Kondo, A. (2002) Direct and efficient production of ethanol from cellulosic material with a yeast strain displaying cellulolytic enzymes. Appl. Environ. Microbiol., 68, 5136-5141. doi: 10.1128/AEM.68.10.5136-5141.2002
Kondo, A., Shigechi, H., Abe, M., Uyama, K., Matsumoto, T., Takahashi, S., Ueda, M., Tanaka, A., Kishimoto, M. and Fukuda, H. (2002) High-level ethanol production from starch by a flocculent Saccharomyces cerevisiae strain displaying cell-surface glucoamylase. Appl. Microbiol. Biotechnol., 58, 291-296. https://doi.org/10.1007/s00253-001-0900-9
Shiraga, S., Ueda, M., Takahashi, S. and Tanaka, A. (2002) Construction of the combinatorial library of Rhizopus oryzae lipase mutated in the lid domain by displaying on yeast cell surface. J. Mol. Catal. B: Enz., 17, 167-173. https://doi.org/10.1016/S1381-1177(02)00024-3
Kera, Y.,Koshiba, K., Hayakawa, S., Kato, T., Tsukada, Y., Ishikawa, H., Itoh, Y., Ibaraki, T., Kawata, K., Takahashi, S. and Yamada, R. (2002) Plasma vitellogenin concentration of juvenile Koi carp (Cyprinus carpio) exposed in situ to effluent from a sewage treatment works. Jpn. J. Environ. Toxicol., 5, 75-89. https://doi.org/10.11403/jset.5.75
Takahashi, S., Ueda, M. and Tanaka, A. (2001) Function of the prosequence for in vivo folding and secretion of active Rhizopus oryzae lipase in Saccharomyces cerevisiae. Appl. Microbiol. Biotechnol., 55, 454-462. https://doi.org/10.1007/s002530000537
Washida, M., Takahashi, S, Ueda, M. and Tanaka, A. (2001) Spacer-mediated display of active lipase on the yeast cell surface. Appl. Microbiol. Biotechnol., 56, 681-686. https://doi.org/10.1007/s002530100718
Matsumoto, T., Takahashi, S., Kaieda, M., Ueda, M., Tanaka, A., Fukuda, H. and Kondo, A. (2001) Yeast whole-cell biocatalyst constructed by intracellular overproduction of Rhizopus oryzae lipase is applicable to biodiesel fuel production. Appl. Microbiol. Biotechnol., 57, 515-520. https://doi.org/10.1007/s002530100733
Shibata, K., Tarui, A., Todoroki, N., Kawamoto, S., Takahashi, S., Kera, Y. and Yamada, R. (2001) Occurrence of N-methyl-L-aspartate in bivalves and its distribution compared with that of N-methy-D-aspartate and D,L-aspartate. Comp. Biochem. Physiol. Part B, 130, 493-500. DOI: 10.1016/s1096-4959(01)00455-9
Kera, Y., Koshiba, K., Kato, T., Hayakawa, S., Takahashi, S., and Yamada, R. (2001) Plasma vitellogenin concentration of wild Koi carp (Cyprinus carpio) in the Shinano River and wetland sites in Niigata Prefecture. Jpn. J. Environ. Toxicol., 4, 35-43. https://doi.org/10.11403/jset.4.35
Takahashi, S., Ueda, M. and Tanaka, A. (2000) Effect of the truncation of the C-terminal region of Kex2 endoprotease on processing of the recombinant Rhizopus oryzae lipase precursor in the co-expression system in yeast. J. Mol. Catal. B: Enz., 10, 233-240. doi: 10.1016/S1381-1177(00)00130-2
Takahashi, S., Ueda, M. and Tanaka, A. (1999) Independent production of two molecular forms of a recombinant Rhizopus oryzae lipase by KEX2-engineered strains of Saccharomyces cerevisiae. Appl. Microbiol. Biotechnol., 52, 534-540. doi: 10.1007/s002530051556
Takahashi, S., Ueda, M., Atomi, H., Beer, H. D., Bornscheuer, U. T., Schmid, R. D. and Tanaka, A. (1998) Extracellular production of active Rhizopus oryzae lipase by Saccharomyces cerevisiae. J. Ferment. Bioeng., 86, 164-168. doi: 10.1016/S0922-338X(98)80055-X